Layers
SPthe

Activation of olfactory ee
Protein Kinases b lb aes

u y To lateral

olfactory

Granule tract

cell layer

Granule
Tee

Odorant binds to Receptor no longer itral/
binds odorants \ ed cell

Mitral f
cell layer!

the receptor

External

Blexifaxm Pen
ayer

glomerular

Gl tul
Proten Kinases Le slaver 4
are no longer Olfactory +.

active nerve layer |
Cribrifprm ee
plate;

Olfactory ann
epithelium! { f
sensory
neuron

FIGURE 3
The negative feedback loop involving receptors and pro-

tein kinases. Note that phospahtases are not included in FIGURE 4

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